Pre-diabetic refers to those individuals who have impaired fasting glucose and who are at increased risk for type 2 diabetes. Also, known as intermediate hyperglycemia, it is a high-risk state where the person will have glycaemic variables higher than normal, but lower than diabetics.
N.C. Mzimela, from the University of Kwa-Zulu Natal, South Africa, has recently identified that there is a progressive deterioration in the structural properties of Red Blood Cells during the prediabetic state. The study is published in the Pakistan Journal of Nutrition.
They studied the Rat model to induce pre-diabetes, using a high-fat high-carbohydrate diet for 20 weeks. By the end of 20 to 32 weeks, the RBC indices were measured. The results suggest significant increases in RBCs, hemoglobin, hematocrit in the prediabetic group. Simultaneously a significant decrease in white blood cell concentration in the prediabetic group was observed.
Findings from this research will pave the way for that suffering from pre-diabetes to understand the changes that might occur at this stage, as it mimics the diet consumed by human beings even though the animals were in a controlled environment. This study will help the researchers and clinicians to uncover the areas of the pre-diabetes stage that many researchers were not able to explore.